This course aims to teach students about efficient and resilient systems in the cognitive era. The learning outcomes include understanding system architectural vision for the cognitive era, cooperative sensor fusion, optimized hardware for embedded AI, achieving high performance and energy efficiency, and statistical modeling of errors in memory. The course covers individual skills such as swarm intelligence, adaptive swarm intelligence, and aggressive GPU under-volting. The teaching method involves lectures and discussions. The intended audience for this course is individuals interested in advanced computer systems and emerging technologies.