This course aims to teach learners about synchronized, multi-sensory integrated learning environments. The learning outcomes include understanding the OHIO principle, time accuracy requirements, programming in cyber-physical networks, and integrating computing and communications. The course covers skills such as programming in distributed systems, designing new computing platforms, and conducting timing characterizations. The teaching method involves lectures, demonstrations, and project work. The intended audience for this course is individuals interested in advanced computing, communication technologies, and programming for cyber-physical systems.